Alexander A. Shcherbakov

University of Washington
Entry year: 2016




J.M. Anderson, B. L. Kier, A. A. Shcherbakov, and N.H. Andersen, “An Improved Capping Unit for Stabilizing the Ends of Associated β-Strand”, FEBS Letters, 588 (24), 4749–4753 (2014). doi: 10.1016/j.febslet.2014.11.006.


J.M. Anderson, B. L. Kier, B. Jurban, A. Byrne, I. Shu, L.A. Eidenschink, A.A. Shcherbakov, M. Hudson, R.M. Fesinmeyer, and N.H. Andersen, “Aryl-Aryl Interactions in Designed Peptide Folds: Spectroscopic Characteristics and Placement Issues for Optimal Structure Stabilization”, Biopolymers, 105 (6), 337 – 356 (2016). doi: 10.1002/bip.22821.


J.M. Anderson, B. Jurban, K.N.L. Huggins, A.A. Shcherbakov, I. Shu, B.L. Kier, and N.H. Andersen, “Nascent Hairpins in Proteins: Identifying Turn Loci and Quantitating Turn Contributions to Hairpin Stability“, Biochemistry, 55 (39), 5537 – 5553 (2016). doi: 10.1021/acs.biochem.6b00732.


J.M. Anderson, A.A. Shcherbakov, B.L. Kier, J. Kellock, I. Shu, A. Byrne, L.A. Eidenschink, and N.H. Andersen, “Optimization of a β-sheet-cap for long loop closure”, Biopolymers, 107 (3) (2017). doi: 10.1002/bip.22995.


J. K. Williams, A. A. Shcherbakov, J. Wang, M. Hong, “Protonation Equilibria and Pore-opening Structure of the Dual-histidine Influenza B Virus M2 Transmembrane Proton Channel from Solid-state NMR“, J. Biol. Chem. 292 (43), 17876-17884 (2017).


M. Roos, T. Wang, A. A. Shcherbakov, M. Hong. “Fast Magic-Angle-Spinning 19F Spin Exchange NMR for Determining Nanometer 19F-19F Distances in Proteins and Pharmaceutical Compounds“, J. Phys. Chem. B 122 (11), 2900-2911 (2018). doi: 10.1021/acs.jpcb.8b00310.


A. A. Shcherbakov, M. Hong. “Rapid Measurement of Long-Range Distances in Proteins by Multidimensional 13C-19F REDOR NMR Under Fast Magic-Angle Spinning“, J. Biomol. NMR 71, 31-43 (2018). doi: 10.1007/s10858-018-0187-0.


A.A. Shcherbakov, V.S. Mandala and M. Hong, “High-Sensitivity Detection of Nanometer 1H-19F Distances for Protein Structure Determination by 1H-Detected Fast MAS NMR”, J. Phys Chem. B, in press (2019).


B. Kwon$, M. Roos$, V.S. Mandala, A.A. Shcherbakov, and M. Hong, “Elucidating Relayed Proton Transfer Through a His-Trp-His Triad of a Transmembrane Proton Channel by Solid-State NMR”, J. Mol. Biol., 431, 2554-2566 (2019).


V.S. Mandala, A.R. Loftis, A.A. Shcherbakov, B.L. Pentelute,  and M. Hong, “Atomic structures of closed and open influenza B M2 proton channel reveal the conduction mechanism”, Nat. Struct. Mol. Biol., 27 (2), 160-167 (2020).


A.A. Shcherbakov, M. Roos, B. Kwon, and M. Hong, “Two-dimensional 19F-13C correlation NMR for 19F resonance assignment of fluorinated proteins”,  J. Biomol. NMR, 74, 193-204 (2020).


A.A. Shcherbakov, G. S. Hisao, V.S. Mandala, N. E. Thomas, M. Soltani, E. A. Salter, J. H. Davis Jr., K. Henzler-Wildman and M. Hong, “Drug-Binding Structure and Drug Dynamics of the Bacterial Transporter EmrE in Lipid Bilayers”, Nat. Comm., 12, 172 (2021).

denotes equal contribution